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货号： bs-20726R-APC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-20726R-APC
- 英文名称
- Anti-CD15/APC
- 中文名称
- APC标记的阶段特异性胚胎表面抗原-1抗体
- 别 名
- Fut4; SSEA-1; 3-FAL; Alpha (1,3) fucosyltransferase; Alpha 13 fucosyltransferase FucT; EC 2.4.1.; ELAM 1 ligand fucosyltransferase; ELAM ligand fucosyltransferase; ELAM1 ligand fucosyltransferase; ELFT; FCT3A; Fuc TIV; Fucosyltransferase 4 alpha 1 3 fucosyltransferase myeloid specific; Fucosyltransferase 4; FucT IV; FUCTIV; FUT4; Galactoside 3 L fucosyltransferase; Lewis X; LeX; SSEA 1; SSEA1; Stage specific embryonic antigen 1; FUC-TIV.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学 细胞膜受体
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse,
- 产品应用
- Flow-Cyt=1:50-200 ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 58kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human CD15
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq].
Function:
May catalyze alpha-1,3 glycosidic linkages involved in the expression of Lewis X/SSEA-1 and VIM-2 antigens.
Subcellular Location:
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi.
Tissue Specificity:
Highest expression in stomach and colon. It is also expressed in the lung, testis, uterus, small intestine and to a lesser extent in spleen, and ovary. Present in trace amounts in brain, thymus, heart, smooth muscle, kidney and bone marrow. Not found in liver, salivary gland and pancreas.
Similarity:
Belongs to the glycosyltransferase 10 family.
Database links:Entrez Gene: 2526 Human
Omim: 104230 Human
SwissProt: P22083 Human
Unigene: 390420 Human
Unigene: 572064 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.