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货号： bs-21291R-APC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-21291R-APC
- 英文名称
- Anti-RBM19/APC
- 中文名称
- APC标记的RNA结合蛋白19抗体
- 别 名
- 1200009A02Rik; AV302714; NPO; Probable RNA-binding protein 19; RBM19; RBM19_HUMAN; RNA-binding motif protein 19.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 信号转导 转录调节因子 结合蛋白 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 108kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human RBM19
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a nucleolar protein that contains six RNA-binding motifs. The encoded protein may be involved in regulating ribosome biogenesis. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Apr 2009]
Function:
Plays a role in embryo pre-implantation development.
Subcellular Location:
Nucleus > nucleolus. Nucleus > nucleoplasm. Cytoplasm. Chromosome. In discrete foci distributed throughout the cytoplasm and nucleoplasm during the 4 to 8 cell stages and the morula stage, but not in the periphery of the nucleolar precursor body (NPB). During blastocyst development, becomes increasingly localized to the nucleolus and less to the cytoplasm. At the late blastocyst stage, localized predominantly in the nucleolus. Localized in the nucleolus during interphase and to the perichromosomal sheath during mitosis. Does not colocalize in the cytoplasm with GW182 in P-bodies. May translocate to the nucleolus upon early embryonic development (By similarity). Colocalizes with NPM1 during interphase. By late prophase, metaphase, anaphase and telophase, associates with the chromosome periphery. By telophase localizes to NPB.
Tissue Specificity:
Expressed in the crypts of Lieberkuhn of the intestine and in intestinal neoplasia (at protein level).
Similarity:
Belongs to the RRM MRD1 family.
Contains 6 RRM (RNA recognition motif) domains.
Database links:Entrez Gene: 9904Human
Entrez Gene: 74111Mouse
Entrez Gene: 304512Rat
SwissProt: Q9Y4C8Human
SwissProt: Q8R3C6Mouse
Unigene: 7482Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.