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货号： bs-12614R-APC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-12614R-APC
- 英文名称
- Anti-Pellino 1/APC
- 中文名称
- APC标记的Pellino 1蛋白抗体
- 别 名
- E3 ubiquitin-protein ligase pellino homolog 1; PELI1; PELI1_HUMAN; Pellino E3 ubiquitin protein ligase 1; Pellino homolog 1; Pellino protein; Pellino-1; Pellino-related intracellular-signaling molecule; Pellino1; PRISM; Protein pellino homolog 1.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 激酶和磷酸酶
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 46kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Pellino 1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- Function:
Scaffold protein involved in the IL-1 signaling pathway via its interaction with the complex containing IRAK kinases and TRAF6. Required for NF-kappa-B activation and IL-8 gene expression in response to IL-1.
Post-translational modifications:
Phosphorylation by IRAK1 and IRAK4 enhances its E3 ligase activity.
Similarity:
Belongs to the pellino family.
Database links:Entrez Gene: 421279Chicken
Entrez Gene: 535054Cow
Entrez Gene: 57162Human
Entrez Gene: 67245Mouse
Entrez Gene: 305549Rat
Entrez Gene: 558420Zebrafish
Omim: 614797Human
SwissProt: Q96FA3Human
SwissProt: Q8C669Mouse
Unigene: 727530Human
Unigene: 28957Mouse
Unigene: 22814Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.