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货号： bs-9969R-APC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-9969R-APC
- 英文名称
- Anti-PDE1C/APC
- 中文名称
- APC标记的磷酸二酯酶1C抗体
- 别 名
- 5-cyclic nucleotide phosphodiesterase 1C; Calcium/calmodulin dependent 35 cyclic nucleotide phosphodiesterase 1C; Calcium/calmodulin-dependent 3; Cam PDE 1C; Cam-PDE 1C; hCam 3; hCam-3; HCAM3; HSPDE1C1A; Human 35 cyclic nucleotide Phosphodiesterase; PDE 1C; Pde1c; PDE1C_HUMAN; Phosphodiesterase 1C; Phosphodiesterase 1C calmodulin dependent; Phosphodiesterase 1C calmodulin dependent 70kDa.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 染色质和核信号 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 81kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human PDE1C
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1C, are calmodulin (see MIM 114180)-dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al., 1992 [PubMed 1326532]).[supplied by OMIM, Oct 2009]
Function:
Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a high affinity for both cAMP and cGMP.
Subcellular Location:
Cytoplasm.
Tissue Specificity:
Expressed in several tissues, including brain and heart.
Similarity:
Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
Database links:Entrez Gene: 5137Human
Entrez Gene: 18575Mouse
Entrez Gene: 81742Rat
Omim: 602987Human
SwissProt: Q14123Human
SwissProt: Q64338Mouse
SwissProt: Q63421Rat
Unigene: 728862Human
Unigene: 5145Mouse
Unigene: 10289Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.