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货号： bs-21057R-APC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-21057R-APC
- 英文名称
- Anti-PPFIBP1/APC
- 中文名称
- APC标记的PTPRF相互作用蛋白结合蛋白1抗体
- 别 名
- PPFIBP 1; hSGT2; hSgt2p; KIAA1230; KIAA1230; L2; LIPB1_HUMAN; Liprin beta 1; liprin related protein; Liprin-beta-1; PPFIBP 1; PPFIBP1; Protein tyrosine phosphatase receptor type f polypeptide interacting protein binding protein 1; Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1; PTPRF interacting protein binding protein 1; PTPRF interacting protein, binding protein 1 (liprin beta 1); PTPRF-interacting protein-binding protein 1; SGT2.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 激酶和磷酸酶 结合蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Zebrafish, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 114kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human PPFIBP1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Function:
May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A.
Tissue Specificity:
Widely expressed. Absent in liver.
Similarity:
Belongs to the liprin family. Liprin-beta subfamily.
Contains 3 SAM (sterile alpha motif) domains.
Database links:Entrez Gene: 101082578Cat
Entrez Gene: 407130Cow
Entrez Gene: 486623Dog
Entrez Gene: 100064684Horse
Entrez Gene: 8496Human
Entrez Gene: 67533Mouse
Entrez Gene: 100516194Pig
Entrez Gene: 312855Rat
Omim: 603141Human
SwissProt: Q86W92Human
SwissProt: Q8C8U0Mouse
Unigene: 172445Human
Unigene: 103382Mouse
Unigene: 22871Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.