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货号： bs-4983R-APC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-4983R-APC
- 英文名称
- Anti-TRIP/APC
- 中文名称
- APC标记的肿瘤坏死因子受体相互作用蛋白抗体
- 别 名
- RING finger protein 206; RNF206; TRAF Interacting Protein; TRAIP; TRIP.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 转录调节因子 细胞膜受体
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 53kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human TRIP
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
RING finger motif and a putative coiled-coil domain. A similar murine protein interacts with TNFR-associated factor 1 (TRAF1), TNFR-associated factor 2 (TRAF2), and cylindromatosis. The interaction with TRAF2 inhibits TRAF2-mediated nuclear factor kappa-B, subunit 1 activation that is required for cell activation and protection against apoptosis.
Function:
Inhibits activation of NF-kappa-B mediated by TNF.
Subunit:
Binds TRAF1 and TRAF2 and is part of the receptor-TRAF signaling complex. Interacts with CYLD.
Subcellular Location:
Cytoplasm. Cytoplasm, perinuclear region.
Similarity:
Contains 1 RING-type zinc finger.
Database links:Entrez Gene: 10293 Human
Omim: 605958 Human
SwissProt: Q9BWF2 Human
Unigene: 517972 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.