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货号： bs-19795R-APC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-19795R-APC
- 英文名称
- Anti-SLC13A3/APC
- 中文名称
- APC标记的溶质载体家族蛋白13成员A3抗体
- 别 名
- +dicarboxylate cotransporter 3; H sapiens mRNA for hepatocyte nuclear factor 4 gamma; hNaDC3; Na; Na(+)/dicarboxylate cotransporter 3; NaDC 3; NaDC-3; NADC3; S13A3_HUMAN; SDCT 2; SDCT2; SLC13A3; Sodium dependent high affinity dicarboxylate transporter 2; Sodium dependent high affinity dicarboxylate transporter 3; Sodium-dependent high-affinity dicarboxylate transporter 2; Solute carrier family 13 (sodium dependent dicarboxylate transporter), member 3; Solute carrier family 13 member 3.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, Cat,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 67kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human SLC13A3
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Mammalian sodium-dicarboxylate cotransporters transport succinate and other Krebs cycle intermediates. They fall into 2 categories based on their substrate affinity: low affinity and high affinity. Both the low- and high-affinity transporters play an important role in the handling of citrate by the kidneys. The protein encoded by this gene represents the high-affinity form. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, although the full-length nature of some of them have not been characterized yet. [provided by RefSeq, Jul 2008]
Function:
High-affinity sodium-dicarboxylate cotransporter that accepts a range of substrates with 4-5 carbon atoms. The stoichiometry is probably 3 Na(+) for 1 divalent succinate.
Subcellular Location:
Cell membrane.
Tissue Specificity:
Expression is highest in kidney. Detected in placenta, brain, liver and pancreas.
Similarity:
Belongs to the SLC13A transporter (TC 2.A.47) family. NADC subfamily.
Database links:Entrez Gene: 526291Cow
Entrez Gene: 485910Dog
Entrez Gene: 64849Human
Entrez Gene: 114644Mouse
Entrez Gene: 100738810Pig
Entrez Gene: 100355238Rabbit
Entrez Gene: 64846Rat
Omim: 606411Human
SwissProt: Q8WWT9Human
SwissProt: Q91Y63Mouse
SwissProt: Q9Z0Z5Rat
Unigene: 655498Human
Unigene: 250738Mouse
Unigene: 3587Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.