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货号： bs-19753R-APC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-19753R-APC
- 英文名称
- Anti-SH3D20/APC
- 中文名称
- APC标记的SH3结构域结合蛋白D20抗体
- 别 名
- ARHGAP27; CAMGAP1; CIN85-associated multi-domain-containing Rho GTPase-activating protein 1; PP905; RHG27_HUMAN; Rho GTPase-activating protein 27; Rho-type GTPase-activating protein 27; SH3 domain containing 20; SH3 domain containing protein 20; SH3D20; SH3P20.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 信号转导 G蛋白信号
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 98kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human SH3D20
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein may pay a role in clathrin-mediated endocytosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2013]
Function:
Rho GTPase-activating protein which may be involved in clathrin-mediated endocytosis. GTPase activators for the Rho-type GTPases act by converting them to an inactive GDP-bound state. Has activity toward CDC42 and RAC1.
Subcellular Location:
Cytoplasm. Membrane.
Tissue Specificity:
Expressed in germinal center B-cell, spleen, chronic lymphocytic leukemia, pancreatic cancer and lung cancer.
Similarity:
Contains 1 PH domain.
Contains 1 Rho-GAP domain.
Contains 1 SH3 domain.
Contains 3 WW domains.
Database links:Entrez Gene: 201176Human
Entrez Gene: 544817Mouse
Entrez Gene: 303583Rat
Omim: 610591Human
SwissProt: Q6ZUM4Human
SwissProt: A2AB59Mouse
SwissProt: Q6TLK4Rat
Unigene: 205326Human
Unigene: 397197Mouse
Unigene: 17895Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.