产品中心
当前位置：首页>产品中心Anti-PXK/APC
货号： bs-19688R-APC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-19688R-APC
- 英文名称
- Anti-PXK/APC
- 中文名称
- APC标记的PXK蛋白抗体
- 别 名
- FLJ20335; K-ATPase; Modulator of Na.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 神经生物学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 65kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human PXK
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a phox (PX) domain-containing protein which may be involved in synaptic transmission and the ligand-induced internalization and degradation of epidermal growth factors. Variations in this gene may be associated with susceptibility to systemic lupus erythematosus (SLE). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Function:
Binds to and modulates brain Na,K-ATPase subunits ATP1B1 and ATP1B3 and may thereby participate in the regulation of electrical excitability and synaptic transmission. May not display kinase activity.
Subcellular Location:
Cytoplasm. Cell membrane. Also associates with the plasma membrane. Isoform 3 is present throughout the cell.
Tissue Specificity:
Widely expressed in all tissues examined except in heart. Isoform 1 is expressed in high levels in the brain, skeletal muscle, spleen and testis. Isoform 7 expression has yet to be demonstrated.
Similarity:
Belongs to the protein kinase superfamily.
Contains 1 protein kinase domain.
Contains 1 PX (phox homology) domain.
Contains 1 WH2 domain.
Database links:Entrez Gene: 614093Cow
Entrez Gene: 54899Human
Entrez Gene: 218699Mouse
Entrez Gene: 306203Rat
Omim: 611450Human
SwissProt: Q7Z7A4Human
SwissProt: Q8BX57Mouse
SwissProt: Q4FZZ1Rat
Unigene: 190544Human
Unigene: 29515Mouse
Unigene: 86175Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.