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货号： bs-19566R-APC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-19566R-APC
- 英文名称
- Anti-OGR1/GPR68/APC
- 中文名称
- APC标记的卵巢癌G蛋白偶联受体1抗体
- 别 名
- G protein coupled receptor 68; G-protein coupled receptor 68; GPR 12A; GPR 68; GPR12A; Gpr68; MGC111379; MGC156983; OGR 1; OGR-1; OGR1; OGR1_HUMAN; Ovarian cancer G protein coupled receptor 1; Ovarian cancer G-protein coupled receptor 1; Sphingosylphosphorylcholine receptor.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 信号转导 G蛋白偶联受体 G蛋白信号
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 41kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human OGR1/GPR68
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- Subunit:
Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca(2+) mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Function also as a metastasis suppressor gene in prostate cancer.
Subcellular Location:
Cell membrane.
Tissue Specificity:
Found at low level in a wide range of tissues, but significantly expressed in lung, kidney, bone and nervous system.
Similarity:
Belongs to the G-protein coupled receptor 1 family.
Database links:Entrez Gene: 8111Human
Entrez Gene: 281799Cow
Entrez Gene: 100688992Dog
Entrez Gene: 101128436Gorilla
Entrez Gene: 100053071Horse
Entrez Gene: 238377Mouse
Entrez Gene: 100153615Pig
Entrez Gene: 100348269Rabbit
Omim: 601404Human
SwissProt: O46685Cow
SwissProt: Q15743Human
SwissProt: Q8BFQ3Mouse
Unigene: 8882Human
Unigene: 32160Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.