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货号： bs-19586R-APC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-19586R-APC
- 英文名称
- Anti-PTGR1/APC
- 中文名称
- APC标记的前列腺素还原酶1抗体
- 别 名
- 15-oxoprostaglandin 13-reductase; FLJ99229; leukotriene B4 12-hydroxydehydrogenase; LTB4DH; MGC34943; NADP-dependent leukotriene B4 12-hydroxydehydrogenase; PGR1; PRG-1; Prostaglandin reductase 1; Ptgr1; PTGR1_HUMAN; RP11-16L21.1; ZADH3; zinc binding alcohol dehydrogenase domain containing 3.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 36kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human PTGR1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes an enzyme that is involved in the inactivation of the chemotactic factor, leukotriene B4. The encoded protein specifically catalyzes the NADP+ dependent conversion of leukotriene B4 to 12-oxo-leukotriene B4. A pseudogene of this gene is found on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]
Function:
Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-oxo-PGE1, 15-oxo-PGE2 and 15-oxo-PGE2-alpha. Has no activity towards PGE1, PGE2 and PGE2-alpha (By similarity). Catalyzes the conversion of leukotriene B4 into its biologically less active metabolite, 12-oxo-leukotriene B4. This is an initial and key step of metabolic inactivation of leukotriene B4.
Subcellular Location:
Cytoplasm.
Tissue Specificity:
High expression in the kidney, liver, and intestine but not in leukocytes.
Similarity:
Belongs to the NADP-dependent oxidoreductase L4BD family.
Database links:Entrez Gene: 22949Human
Entrez Gene: 67103Mouse
Entrez Gene: 192227Rat
Omim: 601274Human
SwissProt: Q14914Human
SwissProt: Q91YR9Mouse
SwissProt: P97584Rat
Unigene: 584864Human
Unigene: 34497Mouse
Unigene: 10656Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.