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货号： bs-20061R-APC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-20061R-APC
- 英文名称
- Anti-phospho-FOXO6 (Ser184)/APC
- 中文名称
- APC标记的磷酸化叉头蛋白O6抗体
- 别 名
- Foxo6 (phospho Ser184); Foxo6 (phospho S184); Forkhead box protein O6; FOXO6_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 转录调节因子 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 51kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthesised phosphopeptide derived from human FOXO6 around the phosphorylation site of Ser184
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Murine Foxo6 is a member of the murine forkhead family of transcription factors. This family consists of over 30 members, the vast majority of which is important in embryonic development. These forkhead transcription factors may play a role in maintenance and survival of developing and adult neurons.
Function:
Transcriptional activator.
Subcellular Location:
Cytoplasmic and Nuclear. When phosphorylated, translocated from nucleus to cytoplasm. High nuclear localization after stimulation with growth factors.
Post-translational modifications:
Phosphorylation of Ser-184 is be important in regulating the transacriptional activity.
Similarity:
Contains 1 fork-head DNA-binding domain.
Database links:Entrez Gene: 100132074Human
Entrez Gene: 329934Mouse
Entrez Gene: 313558Rat
Omim: 611457Human
SwissProt: A8MYZ6Human
SwissProt: Q70KY4Mouse
Unigene: 277090Mouse
Unigene: 190858Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.