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货号： bs-13882R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-13882R-PE-Cy7
- 英文名称
- Anti-CGREF1/PE-Cy7
- 中文名称
- PE-Cy7标记的细胞生长调节蛋白CGREF1抗体
- 别 名
- Cell growth regulator with EF hand domain 1; Cell growth regulator with EF hand domain protein 1; Cell growth regulatory gene 11; Cell growth regulatory gene 11 protein; CGR 11; CGR11; CGRE1_HUMAN; CGREF 1; CGREF1; Hydrophobestin.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 细胞周期蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 30kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human CGREF1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
CGREF1 (cell growth regulator with EF-hand domain 1), also known as CGR11, is a 301 amino acid secreted protein that contains two highly conserved calcium binding EF-hand domains, which are required for mediating cell-cell adhesion. Induced by p53, CGREF1 is able to inhibit cell growth in various cell lines. CGREF1 is encoded by a gene located on human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes. Additionally, an extremely rare recessive genetic disorder, Alstrom syndrome, is caused by mutations in the ALMS1 gene, which maps to chromosome 2.
Function:
Mediates cell-cell adhesion in a calcium-dependent manner (By similarity). Able to inhibit growth in several cell lines.
Subunit:
Secreted (By similarity).
Similarity:
Contains 2 EF-hand domains.
Database links:Entrez Gene: 10669Human
Omim: 606137Human
SwissProt: Q99674Human
Unigene: 159525Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.