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货号： bs-13760R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-13760R-PE-Cy7
- 英文名称
- Anti-DCL-1/PE-Cy7
- 中文名称
- PE-Cy7标记的C型凝集素受体CLEC13A抗体
- 别 名
- CD302; CLEC13A; DCL1; C-type lectin domain family 13 member A; C-type lectin BIMLEC; CD302_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 细胞粘附分子 细胞表面分子
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Horse, Rabbit,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 26kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human DCL-1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.
- 产品介绍
- background:
DCL-1 is a 232 amino acid single-pass type I membrane protein involved in endocytosis, phagocytosis and cell adhesion and migration. A C-type lectin receptor, DCL-1 is widely expressed with highest levels found in peripheral blood, myeloid and B lymphoid cell lines, liver, ovary and lung. DCL-1 undergoes alternative splicing to produce three isoforms designated DCL-1 isoform 1, isoform 2 (also known as fusion protein variant V34-2) and isoform 3 (also designated fusion protein variant V33-2). DCL-1 isoforms 2 and 3 are produced in malignant lympoma cells, known as Hodgkin and Reed-Sternberg (HRS) cells. DCL-1 contains one C-type lectin domain and is encoded by a gene that maps to human chromosome 2q24.2. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alstr鰉 syndrome.
Function:
Expressed in myeloid and B lymphoid cell lines. Isoform 2 and isoform 3 are expressed in malignant Hodgkin lymphoma cells called Hodgkin and Reed-Sternberg (HRS) cells.
Subcellular Location:
Membrane.
Similarity:
Contains 1 C-type lectin domain.
Database links:Entrez Gene: 9936Human
Entrez Gene: 66205Mouse
Entrez Gene: 295629Rat
Omim: 612246Human
SwissProt: Q8IX05Human
SwissProt: Q9DCG2Mouse
SwissProt: Q5FVR3Rat
Unigene: 130014Human
Unigene: 674903Human
Unigene: 227281Mouse
Unigene: 98436Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.