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货号: bs-15593R-PE-Cy7 基本售价: 2980.0 元 规格: 100ul
产品信息
- 产品编号
- bs-15593R-PE-Cy7
- 英文名称
- Anti-OAZ1/PE-Cy7
- 中文名称
- PE-Cy7标记的鸟氨酸脱羧酶抗酶1抗体
- 别 名
- Antizyme 1; Antizyme; AZI; MGC138338; OAZ 1; OAZ; OAZ1; OAZ1_HUMAN; ODC Az; ODC-Az; Ornithine decarboxylase antizyme 1; Ornithine decarboxylase antizyme.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学 信号转导 新陈代谢
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 25kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human OAZ1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- Function:
Binds to, and destabilizes, ornithine decarboxylase which is then degraded. Also inhibits cellular uptake of polyamines by inactivating the polyamine uptake transporter. SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1.
Subunit:
Forms a ternary complex with PSMB4 and OAZ1 before PSMB4 is incorporated into the 20S proteasome.
Similarity:
Belongs to the ODC antizyme family.
Database links:Entrez Gene: 4946 Human
Entrez Gene: 18245 Mouse
Entrez Gene: 25502 Rat
Omim: 601579 Human
SwissProt: P54368 Human
SwissProt: P54369 Mouse
SwissProt: P54370 Rat
Unigene: 446427 Human
Unigene: 398119 Mouse
Unigene: 266 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.