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货号： bs-13723R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-13723R-PE-Cy7
- 英文名称
- Anti-PCDH10/PE-Cy7
- 中文名称
- PE-Cy7标记的原钙粘附蛋白10抗体
- 别 名
- DKFZp761O2023; KIAA1400; MGC133344; OL PCDH; Ortholog of OL pcdh; OTTHUMP00000220001; PCD10_HUMAN; PCDH10; PCDH19; Protocadherin 10; Protocadherin-10.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 神经生物学 信号转导 细胞粘附分子
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Pig, Cow, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 110kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human PCDH10
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDH10 (protocadherin 10), also known as PCDH19 or OL-PCDH, is a 1,040 amino acid single-pass type I membrane protein that contains six cadherin domains and one transmembrane domain. Expressed at moderate levels in brain, ovary and testis and present at lower levels in all other tissues, PCDH10 functions as a calcium-dependent cell-adhesion protein that may function as a tumor suppressor. When underexpressed, PCDH10 is associated with the progression of various carcinomas, including gastric cancer.
Function:
Potential calcium-dependent cell-adhesion protein.
Subcellular Location:
Cell membrane.
Tissue Specificity:
Moderately expressed in all regions of the brain examined, as well as in testis and ovary, and low expression in all other tissues tested.
Similarity:
Contains 6 cadherin domains.
Database links:Entrez Gene: 57575Human
Entrez Gene: 531875Cow
Entrez Gene: 18526Mouse
Omim: 608286Human
SwissProt: Q9P2E7Human
Unigene: 192859Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.