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货号： bs-13659R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-13659R-PE-Cy7
- 英文名称
- Anti-PACSIN3/PE-Cy7
- 中文名称
- PE-Cy7标记的胞浆蛋白PACSIN3抗体
- 别 名
- Endophilin 1; Endophilin I; FLJ17861; OTTHUMP00000234262; OTTHUMP00000234263; OTTHUMP00000234264; PACN3_HUMAN; Pacsin3; Protein kinase C and casein kinase substrate in neurons 3; Protein kinase C and casein kinase substrate in neurons protein 3; SDPIII; SH3 domain containing protein 6511; SH3 domain-containing protein 6511; syndapin III;
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 神经生物学 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Cow, Horse, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 48kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human PACSIN3
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Plays a role in endocytosis and regulates internalization of plasma membrane proteins. Overexpression impairs internalization of SLC2A1/GLUT1 and TRPV4 and increases the levels of SLC2A1/GLUT1 and TRPV4 at the cell membrane. Inhibits the TRPV4 calcium channel activity (By similarity).
Function:
May play a role in vesicle formation and transport.
Subcellular Location:
Cytoplasm. Cell membrane. Detected at the inner aspect of the plasma membrane in cells or myotubes.
Tissue Specificity:
Expressed in heart and skeletal muscle, lung, kidney, adrenal gland and placenta.
Post-translational modifications:
Phosphorylated by casein kinase 2 (CK2) and protein kinase C (PKC).
Similarity:
Belongs to the PACSIN family.
Contains 1 FCH domain.
Contains 1 SH3 domain.
Database links:Entrez Gene: 29763Human
Entrez Gene: 80708Mouse
Omim: 606513Human
SwissProt: Q9UKS6Human
SwissProt: Q99JB8Mouse
Unigene: 334639Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.