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货号： bs-13605R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-13605R-PE-Cy7
- 英文名称
- Anti-ZNF206/PE-Cy7
- 中文名称
- PE-Cy7标记的锌指蛋白206抗体
- 别 名
- Zfp206; Zinc finger and SCAN domain-containing protein 10; Zinc Finger Protein 206; ZSCAN10; ZSC10_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 神经生物学 干细胞 转录调节因子 锌指蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Cow, Horse,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 80kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human ZNF206
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF206 (zinc finger protein 206), also known as ZSCAN10 (zinc finger and SCAN domain containing 10), is a 725 amino acid protein that contains one SCAN box domain and 14 C2H2-type zinc fingers. Localized to the nucleus, ZNF206 is thought to play a role in transcriptional regulation events. The gene encoding ZNF206 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohns disease, which is a gastrointestinal inflammatory condition.
Function:
Znf206 is a zinc finger protein and probable transcriptional regulator. It is expressed in embryonic stem cells and downregulated upon differentiation. Both Oct4 and Sox2 bind the znf206 gene.
Subunit:
Interacts with POU5F1/OCT4 and SOX2 (By similarity).
Subcellular Location:
Nuclear
Similarity:
Contains 14 C2H2-type zinc fingers.
Contains 1 SCAN box domain.
Database links:Entrez Gene: 84891Human
Entrez Gene: 332221Mouse
SwissProt: Q96SZ4Human
SwissProt: Q20D61Mouse
Unigene: 334515Human
Unigene: 270315Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.