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货号： bs-13599R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-13599R-PE-Cy7
- 英文名称
- Anti-HoxC13/PE-Cy7
- 中文名称
- PE-Cy7标记的同源盒蛋白HOX13抗体
- 别 名
- ECTD9; Homeo box 3G; Homeo box C13; homeobox C13; Homeobox protein Hox 3G; Homeobox protein Hox-C13; Hox-3G; HOX3; HOX3G; HOXC13; HXC13; NUP98.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 干细胞 转录调节因子 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 35kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human HoxC13
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The Hox proteins are a family of transcription factors that play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. Hox proteins are involved in controlling axial patterning, leukemias and hereditary malformations. HoxC13 (homeobox C13), also known as HOX3 or HOX3G, is a 330 amino acid protein that contains one homeobox DNA-binding domain and is a member of the Abd-B homeobox family. Localized to the nucleus, HoxC13 functions as a sequence-specific transcription factor that, in conjunction with a variety of other proteins, provides cells with positional identities on their anterior-posterior axis. Via its ability to modify features of the anterior-posterior body axis, HoxC13 is thought to play a role in the development of nails, hair and filiform papilla.
Function:
HOXC13 is a member of a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms and provide cells with specific positional identities on the anterior-posterior axis. HOXC13 is a sequence-specific transcription factor that may play a role in the development of hair, nail, and filiform papilla.
Subcellular Location:
Nuclear
Similarity:
Belongs to the Abd-B homeobox family.
Contains 1 homeobox DNA-binding domain.
Database links:Entrez Gene: 3229Human
Entrez Gene: 538716Cow
Entrez Gene: 15422Mouse
Omim: 142976Human
SwissProt: P31276Human
SwissProt: P50207Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.