产品中心
当前位置：首页>产品中心Anti-IFT140/PE-Cy7
货号： bs-15559R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-15559R-PE-Cy7
- 英文名称
- Anti-IFT140/PE-Cy7
- 中文名称
- PE-Cy7标记的细胞纤毛内转运同源蛋白140抗体
- 别 名
- Gs114; Intraflagellar transport 140 homolog (Chlamydomonas); WD and tetratricopeptide repeats protein 2; IF140_HUMAN; WDTC2.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Horse,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 165kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human IFT140
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
IFT140 is a gene encodes one of the subunits of the intraflagellar transport (IFT) complex A. Intraflagellar transport is involved in the genesis, resorption and signaling of primary cilia. The primary cilium is a microtubule-based sensory organelle at the surface of most quiescent mammalian cells, that receives signals from its environment, such as the flow of fluid, light or odors, and transduces those signals to the nucleus. Loss of the corresponding protein in mouse results in renal cystic disease.
Function:
Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport. Plays a pivotal role in proper development and function of ciliated cells. Involved in ciliogenesis and cilia maintenance.
Subunit:
Component of the IFT complex A (IFT-A).
Subcellular Location:
Cytoplasm, cytoskeleton, cilium basal body.
DISEASE:
Mainzer-Saldino syndrome (MZSDS) [MIM:266920]: A rare autosomal recessive disease characterized by phalangeal cone-shaped epiphyses, chronic renal disease, nearly constant retinal dystrophy, and mild radiographic abnormality of the proximal femur. Occasional features include short stature, cerebellar ataxia, and hepatic fibrosis. Note=The disease is caused by mutations affecting the gene represented in this entry.
Similarity:
Contains 9 TPR repeats.
Contains 5 WD repeats.
Database links:Entrez Gene: 9742 Human
Entrez Gene: 106633 Mouse
SwissProt: Q96RY7 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.