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货号： bs-15561R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-15561R-PE-Cy7
- 英文名称
- Anti-IFT20/PE-Cy7
- 中文名称
- PE-Cy7标记的细胞纤毛内转运同源蛋白20抗体
- 别 名
- hIFT20; Intraflagellar transport 20 homolog (Chlamydomonas); Intraflagellar transport protein 20 like; IFT20_HUMAN; Intraflagellar transport protein IFT20.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 15kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human IFT20
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
IFT20 is a gene encodes a intraflagellar transport protein important for intracellular transport. The encoded protein forms part of a complex involved in trafficking of proteins from the Golgi body, including recycling of immune signalling components (Finetti et al., PubMed: 19855387). This gene is part of a complex set of sense-antisense loci that may be co-regulated. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 14.
Function:
Part of intraflagellar transport (IFT) particles involved in ciliary process assembly. May play a role in the trafficking of ciliary membrane proteins from the Golgi complex to the cilium.
Subunit:
Component of IFT complex B composed of IFT88, IFT57, TRAF3IP1, IFT52, IFT27, HSPB11 and IFT20. Interacts directly with IFT57 and KIF3B/Kinesin II subunit (By similarity). Interacts with CCDC41/CEP83.
Subcellular Location:
Golgi apparatus, cis-Golgi network (By similarity). Cytoplasm, cytoskeleton, centrosome, centriole (By similarity). Cytoplasm, cytoskeleton, cilium basal body (By similarity). Note=Present at the centrosomes during the cell cycle and associated with the proximal portion of the mother centriole and the lateral aspect of the daughter centriole. Associated with basal body at the base of primary cilia (By similarity).
Tissue Specificity:
Expressed in almost all tissues.
Database links:
UniProtKB/Swiss-Prot: Q8IY31.1
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.