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货号： bs-15565R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-15565R-PE-Cy7
- 英文名称
- Anti-IFT81/PE-Cy7
- 中文名称
- PE-Cy7标记的细胞纤毛内转运同源蛋白81抗体
- 别 名
- Carnitine deficiency associated expressed in ventricle 1 isoform 2; Carnitine deficiency-associated protein expressed in ventricle 1; CDV-1; CDV1; CDV1R; Ift81; IFT81_HUMAN; intraflagellar transport 81 homolog (Chlamydomonas); Intraflagellar transport protein 81 homolog.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 80kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human IFT81
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
IFT81 is a 676 amino acid protein that is present at high levels in testis and is moderately expressed in heart, liver, ovary, pancreas, kidney and skeletal muscle. Existing as three alternatively spliced isoforms, two of which are designated CDV-1 and CDV-1R, IFT81 plays a role in testicular development and spermatogenesis and may also be involved in cardiac hypertrophy caused by carnitine deficiency. The gene encoding IFT81 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and Trisomy 12p, which causes facial developmental defects and seizure disorders.
Function:
Isoform CDV-1 may be involved in cardiac hypertrophy caused by carnitine deficiency (By similarity).
Isoform CDV-1R appears to play a role in development of the testis and spermatogenesis (By similarity).
Tissue Specificity:
Highly expressed in testis, moderately in ovary, heart, liver, skeletal muscle, kidney and pancreas, low in prostate, brain, placenta and lung and not detected in spleen, thymus, small intestine and colon. Isoform CDV-1R is abundantly expressed in testis.
Database links:Entrez Gene: 28981Human
SwissProt: Q8WYA0Human
Unigene: 528382Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.