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货号： bs-10182R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-10182R-PE-Cy7
- 英文名称
- Anti-FUT5/PE-Cy7
- 中文名称
- PE-Cy7标记的FUT5抗体
- 别 名
- UT5_HUMAN; Alpha-(1,3)-fucosyltransferase; Fucosyltransferase 5; Fucosyltransferase V; Fuc-TV; FucT-V; Galactoside 3-L-fucosyltransferase.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 41kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human FUT5
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The protein encoded by this gene belongs to the glycosyltransferase family. It is localized to the golgi, and catalyzes the last step in the biosynthesis of Lewis X (LeX) antigen, the addition of a fucose to precursor polysaccharides. This protein is one of the few fucosyltransferases that synthesizes the LeX oligosaccharide (CD15) expressed in the organ buds progressing in mesenchyma during embryogenesis. It is also responsible for the expression of CD15 in mature granulocytes. A common haplotype of this gene has also been associated with susceptibility to placental malaria infection. [provided by RefSeq, Nov 2011]
Function:
May catalyze alpha-1,3 glycosidic linkages involved in the expression of VIM-2, Lewis X/SSEA-1 and sialyl Lewis X antigens.
Subcellular Location:
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi.
Tissue Specificity:
Liver, colon and testis and trace amounts in T-cells and brain.
Similarity:
Belongs to the glycosyltransferase 10 family.
Database links:Entrez Gene: 10690 Human
Entrez Gene: 2526 Human
Entrez Gene: 2527 Human
Entrez Gene: 2528 Human
Entrez Gene: 2529 Human
Omim: 136835 Human
SwissProt: P22083 Human
SwissProt: P51993 Human
SwissProt: Q11128 Human
SwissProt: Q11130 Human
SwissProt: Q9Y231 Human
Unigene: 390420 Human
Unigene: 457 Human
Unigene: 49117 Human
Unigene: 572064 Human
Unigene: 623098 Human
Unigene: 631843 Human
Unigene: 631846 Human
Unigene: 705615 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.