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货号： bs-10383R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-10383R-PE-Cy7
- 英文名称
- Anti-FGFR substrate 3/PE-Cy7
- 中文名称
- PE-Cy7标记的纤维母细胞生长因子受体底物3抗体
- 别 名
- FGFR signalling adaptor SNT2; FGFR substrate 3; Fibroblast growth factor receptor substrate 3; FRS2 beta; FRS2B; FRS3; FRS3 protein; MGC17167; SNT 2; Suc1 associated neurotrophic factor target 2 (FGFR signalling adaptor); Suc1 associated neurotrophic factor target 2; FRS3_HUMAN; FGFR-signaling adaptor SNT2; Suc1-associated neurotrophic factor target 2; SNT-2.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 信号转导 生长因子和激素
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Cow, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 54kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human FGFR substrate 3
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The protein encoded by this gene is a substrate for the fibroblast growth factor receptor. It is found in peripheral plasma membrane and functions in linking FGF receptor stimulation to activators of Ras. [provided by RefSeq, Jul 2008].
Function:
Adapter protein that links FGF and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2.
Subunit:
Binds NTRK1. Binds FGFR1, NGFR, GRB2, PTPN11 and ERK2.
Subcellular Location:
Membrane; Lipid-anchor.
Tissue Specificity:
Phosphorylated by ULK2 in vitro. Phosphorylated on tyrosine residues upon stimulation by BFGF or NGFB.
Similarity:
Contains 1 IRS-type PTB domain.
Database links:Entrez Gene: 10817 Human
Entrez Gene: 107971 Mouse
Entrez Gene: 316213 Rat
Omim: 607744 Human
SwissProt: O43559 Human
SwissProt: Q91WJ0 Mouse
SwissProt: Q52RG8 Rat
Unigene: 194208 Human
Unigene: 34398 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.