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货号： bs-15465R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-15465R-PE-Cy7
- 英文名称
- Anti-HERPUD2/PE-Cy7
- 中文名称
- PE-Cy7标记的HERPUD蛋白家族成员2抗体
- 别 名
- FLJ22313; FLJ31032; HERP2_HUMAN; HERPUD 2; HERPUD family member 2; HERPUD2; Homocysteine inducible endoplasmic reticulum stress inducible ubiquitin like domain member 2; Homocysteine responsive endoplasmic reticulum resident ubiquitin like domain member 2 protein; Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein; OTTHUMP00000158869.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 45kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human HERPUD2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The endoplasmic reticulum (ER) stress response is triggered by the accumulation of unfolded proteins within the ER and is characterized by three events: the inhibition of translation (to prevent further protein accumulation), the up-regulated expression of polypeptide-folding proteins (known as the unfolded protein response or UPR) and the degradation of misfolded proteins by the ER-associated protein degradation (ERAD) system. Members of the homocysteine-inducible and ER stress-inducible ubiquitin-like domain families are components of the ERAD system and, via their ubiquitin-like domain, are thought to be involved in the destruction of misfolded proteins. HERPUD2 (Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2) is a 406 amino acid single-pass membrane protein containing one N-terminal ubiquitin-like domain. HERPUD2 is thought to be involved in the unfolded protein response (UPR) pathway.
Function:
Could be involved in the unfolded protein response (UPR) pathway (By similarity).
Subcellular Location:
Membrane; Single-pass membrane protein (Potential).
Similarity:
Contains 1 ubiquitin-like domain.
Database links:Entrez Gene: 64224 Human
Entrez Gene: 80517 Mouse
Entrez Gene: 300463 Rat
SwissProt: Q9BSE4 Human
SwissProt: Q9JJC9 Mouse
SwissProt: Q66HH4 Rat
Unigene: 643051 Human
Unigene: 142843 Mouse
Unigene: 231721 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.