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货号： bs-15360R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-15360R-PE-Cy7
- 英文名称
- Anti-GPR30/PE-Cy7
- 中文名称
- PE-Cy7标记的G蛋白偶联受体GPR30蛋白抗体
- 别 名
- CEPR; Chemoattractant receptor-like 2; CMKRL2; FEG-1; Flow-induced endothelial G protein-coupled receptor; Flow-induced endothelial G-protein coupled receptor 1; G protein-coupled receptor 30; G-protein coupled estrogen receptor 1; G-protein coupled receptor 30; GPCR-Br; Gper; GPER_HUMAN; GPR30; IL8-related receptor DRY12; Lergu; LERGU2leucine rich protein in GPR30 3UTR; LYGP; RLymphocyte-derived G-protein coupled receptor; Membrane estrogen receptor; mER; MGC99678; GPCR 30.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 染色质和核信号 神经生物学 信号转导 G蛋白偶联受体 新陈代谢 表观遗传学 G蛋白信号
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human,
- 产品应用
- Flow-Cyt=1:50-200 ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 42kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human GPR30
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized. [provided by RefSeq, Jul 2008]
Function:
Receptor for estrogen.
Subcellular Location:
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity). Golgi apparatus membrane; Multi-pass membrane protein (By similarity). Note=Protein has been detected in the cell membrane, endoplasmic reticulum and Golgi apparatus. It is currently unclear whether this is a cell surface or intracellular receptor.
Tissue Specificity:
Ubiquitously expressed, but is most abundant in placenta. In brain regions, expressed as a 2.8 kb transcript in basal forebrain, frontal cortex, thalamus, hippocampus, caudate and putamen.
Similarity:
Belongs to the G-protein coupled receptor 1 family.
Database links:Entrez Gene: 2852Human
Entrez Gene: 76854Mouse
Entrez Gene: 171104Rat
Omim: 601805Human
SwissProt: Q99527Human
SwissProt: Q8BMP4Mouse
SwissProt: O08878Rat
Unigene: 20961Human
Unigene: 389706Mouse
Unigene: 9806Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.