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货号： bs-13553R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-13553R-PE-Cy7
- 英文名称
- Anti-ZBED3/PE-Cy7
- 中文名称
- PE-Cy7标记的锌指蛋白BED3抗体
- 别 名
- MGC15435; ZBED3; ZBED3_HUMAN; Zinc finger BED domain containing 3; Zinc finger BED domain-containing protein 3; Zinc finger BED type containing 3.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 干细胞 锌指蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 25kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human ZBED3
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- Function:
Acts as a positive regulator in the activation of the canonical Wnt/beta-catenin signaling pathway by stabilizing cytoplasmic beta-catenin. Involved in transcription activation of Wnt target gene expression.
Subunit:
Interacts with AXIN1; the interaction is direct, enhanced by protein kinase GSK3B and casein kinase CSNK1E activities and decreases GSK3B-induced beta-catenin serine and threonine phosphorylations.
Subcellular Location:
Cytoplasm. Membrane. Note=Colocalizes with AXIN1 in the cytoplasm.
Similarity:
Contains 1 BED-type zinc finger.
Database links:Entrez Gene: 84327Human
Entrez Gene: 72114Mouse
Entrez Gene: 361881Rat
SwissProt: Q96IU2Human
Unigene: 584988Human
Unigene: 3774Mouse
Unigene: 103511Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.