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货号： bs-13484R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-13484R-PE-Cy7
- 英文名称
- Anti-GOLGA7/PE-Cy7
- 中文名称
- PE-Cy7标记的高尔基体膜相关蛋白7抗体
- 别 名
- GCP 16; GCP16; GOLGA 7; GOLGA3AP1; GOLGA7A; Golgi autoantigen golgin subfamily a 7; Golgi complex associated protein of 16kDa; Golgin A7; Golgin subfamily A member 7; HSPC041; MGC21096; MGC4876; GOGA7_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 细胞类型标志物
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 16kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human GOLGA7
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
GOLGA7 is a multi-pass membrane protein belonging to the Erf4 family of proteins. It is the functional ortholog of the yeast Erf4 protein. Localizing to the Golgi apparatus, GOLGA7 is a widely expressed protein but its expression is absent from colon and thymus tissues. GOLGA7 is palmitoylated on two cysteine residues, and this palmitoylation is required for its interaction with golgin 160 and its Golgi-localization. GOLGA7 also forms a complex with ZDHHC9 and, together, these proteins function as a Ras palmitoyltransferase (Ras PAT) which is required for palmitoylation of H-Ras and N-Ras proteins. The palmitoylation of Ras proteins is essential for the trafficking of Ras proteins from the Golgi to the plasma membrane, thus implicating GOLGA7 in protein transport from the Golgi to the cell surface.
Function:
GOLGA7 (Golgi autoantigen, golgin subfamily a, 7) is a member of the golgin family and may be involved in protein transport from the Golgi to the cell surface. GOLGA7 forms a protein complex with ZDHHC9. This ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for H-RAS and N-RAS.
Subunit:
Interacts with GOLGA3. Interacts with ZDHHC9.
Subcellular Location:
Golgi apparatus membrane; Lipid-anchor
Tissue Specificity:
Expressed in all tissues except colon and thymus.
Post-translational modifications:
Palmitoylated on Cys-69 and Cys-72; which is required for Golgi localization and interaction with GOLGA3.
Similarity:
Belongs to the ERF4 family.
Database links:
UniProtKB/Swiss-Prot: Q7Z5G4.2
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.