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货号： bs-13388R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-13388R-PE-Cy7
- 英文名称
- Anti-GLUT6/GLUT9/PE-Cy7
- 中文名称
- PE-Cy7标记的葡萄糖转运蛋白6抗体
- 别 名
- Glucose Transporter GLUT6; A330096C23; F630103L12Rik; Glucose transporter type 6; Glucose transporter type 9; GLUT-6; GLUT-9; Glut6; Glut9; GTR6_HUMAN; HSA011372; RP23-449M10.2; SLC2A6; Solute carrier family 2, facilitated glucose transporter member 6.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 神经生物学 信号转导 新陈代谢
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 55kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human GLUT6/Glucose Transporter GLUT6
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The oxidation of glucose functions as the dominant source of metabolic energy for mammals. The plasma membrane is impermeable to glucose, so the cellular uptake of this important nutrient is achieved by facultative hexose transproters (Gluts). Gluts are integral membrane proteins that transport glucose and related hexoses. Glucose binds to a Glut on one side of the membrane which provokes a conformational change causing it to release glucose to the other side. Members of the Glut family may enhance the metabolic activity of tumor cells. Glut6 is part of the third out of three classes of Gluts. Glut6 is mainly expressed in the brain, spleen and peripheral leukocytes. It appears to be regulated by subcellular redistribution, because it is targeted to intracellular compartments by di-leucine motifs, recycling itself in a Dynamin-dependent manner.
Function:
Facilitative glucose transporter; binds cytochalasin B with low affinity.
Subcellular Location:
Cell membrane. The dileucine internalization motif is critical for intracellular sequestration.
Tissue Specificity:
Highly expressed in brain, spleen and peripheral blood leukocytes.
Similarity:
Belongs to the major facilitator superfamily.
Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
Database links:Entrez Gene: 11182 Human
Omim: 606813 Human
SwissProt: Q9UGQ3 Human
Unigene: 244378 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.