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货号: bs-13441R-PE-Cy7 基本售价: 2980.0 元 规格: 100ul
产品信息
- 产品编号
- bs-13441R-PE-Cy7
- 英文名称
- Anti-GSTT2/PE-Cy7
- 中文名称
- PE-Cy7标记的谷胱甘肽S转移酶θ2抗体
- 别 名
- Glutathione S Transferase theta 2; EC 2.5.1.18; Glutathione S transferase 12; Glutathione S transferase Yrs Yrs; Glutathione S-transferase theta-2; Glutathione S-transferase theta-2B; GST 12 12; GST class theta 2; GST class-theta-2; GST T2; GSTT 2; GSTT2; GSTT2 protein; GSTT2_HUMAN; GSTT2B; MGC182032; OTTHUMP00000198491; OTTHUMP00000198492.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 信号转导 新陈代谢
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 27kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human GSTT2/Glutathione S Transferase theta 2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Glutathione (GSH) is a tripeptide antioxidant which reduces disulfide bonds between cytoplasmic proteins. The constitutive enzyme glutathione reductase transforms glutathione into its reduced state which ultimately can provide a measure of cellular toxicity. GSTT2 (glutathione S-transferase theta-2), also known as GST class-theta-2, is a 244 amino acid enzyme with sulfatase activity that functions in conjugating reduced glutathione to hydrophobic electrophiles. GSTT2 exists as a homodimer in the cytoplasm and is expressed in low levels in the liver and the lung. GSTT2 belongs to the GST superfamily and contains both a GST C-terminal and a GST N-terminal domain. The gene encoding GSTT2 exists on human chromosome 22.
Function:
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a sulfatase activity.
Subunit:
Homodimer.
Subcellular Location:
Cytoplasm.
Tissue Specificity:
Expressed at low levels in liver. In lung, expressed at low levels in ciliated bronchiolar cells, alveolar macrophages and alveolar type II cells.
Similarity:
Belongs to the GST superfamily. Theta family.
Contains 1 GST C-terminal domain.
Contains 1 GST N-terminal domain.
Database links:
UniProtKB/Swiss-Prot: P0CG30.1
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.