产品中心
当前位置：首页>产品中心Anti-GLI4/PE-Cy7
货号： bs-13373R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-13373R-PE-Cy7
- 英文名称
- Anti-GLI4/PE-Cy7
- 中文名称
- PE-Cy7标记的转录因子Gli4/锌指蛋白gli4抗体
- 别 名
- GLI 4; GLI Kruppel family member GLI 4; GLI Kruppel family member GLI4; GLI4; GLI4_HUMAN; HKR 4; HKR4; HKR4 protein; Krueppel related zinc finger protein 4; Krueppel-related zinc finger protein 4; Neural specific DNA binding protein; Oncogene HKR 4; Oncogene HKR4; Protein HKR 4; Protein HKR4; Zinc finger protein GLI 4; Zinc finger protein GLI4.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 转录调节因子 锌指蛋白 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Cow, Horse,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 41kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human GLI4
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a krueppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. GLI-4, also known as HKR4, is a 376 amino acid protein that localizes to the nucleus and contains seven C2H2-type zinc fingers. Belonging to the krueppel C2H2-type zinc-finger protein family, GLI-4 may function as a transcriptional regulator, effectively activating or repressing the transcription of target genes. The gene encoding GLI-4 maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies.
Subcellular Location:
Nucleus.
Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 7 C2H2-type zinc fingers.
Database links:Entrez Gene: 2738 Human
Omim: 165280 Human
SwissProt: P10075 Human
Unigene: 400533 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.