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货号： bs-13342R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-13342R-PE-Cy7
- 英文名称
- Anti-GFPT2/PE-Cy7
- 中文名称
- PE-Cy7标记的D-果糖6磷酸转移酶2抗体
- 别 名
- D fructose 6 phosphate amidotransferase 2; GFAT 2; GFAT2; Glucosamine fructose 6 phosphate aminotransferase [isomerizing] 2; glutamine fructose 6 phosphate transaminase 2; Glutamine:fructose 6 phosphate amidotransferase 2; Hexosephosphate aminotransferase 2; GFPT2_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 心血管 细胞生物 信号转导 新陈代谢
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 77kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human GFPT2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
GFPT2 (glutamine-fructose-6-phosphate transaminase 2), also known as D-fructose-6-phosphate amidotransferase 2 or hexosephosphate aminotransferase 2, is a 682 amino acid protein and isoenzyme of GFAT1, the first and rate-limiting enzyme for the entry of glucose into the hexosamine biosynthetic pathway (HBP), which is a relatively minor branch of glycolysis. Expressed in spinal cord, heart and placenta, GFAT2 regulates glucose entry into the HBP and likely controls the availability of precursors for N- and O-linked protein glycosylation. Containing one glutamine amidotransferase type-2 domain and two SIS domains. GFAT2 is encoded by a gene that maps to human chromosome 5q35.3. GFAT2 gene variants have been linked to type 2 diabetes, diabetic nephropathy, and increased GFPT2 mRNA levels.
Function:
GFPT2, also known as glutamine fructose 6 phosphate transaminase 2, controls the flux of glucose into the hexosamine pathway. It is probably involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins.
Tissue Specificity:
Highest levels of expression in heart, placenta, and spinal cord.
Similarity:
Contains 1 glutamine amidotransferase type-2 domain.
Contains 2 SIS domains.
Database links:Entrez Gene: 9945 Human
Entrez Gene: 14584 Mouse
Entrez Gene: 360518 Rat
Omim: 603865 Human
SwissProt: O94808 Human
SwissProt: Q9Z2Z9 Mouse
SwissProt: Q4KMC4 Rat
Unigene: 696497 Human
Unigene: 24402 Mouse
Unigene: 16089 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.