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货号: bs-13355R-PE-Cy7 基本售价: 2980.0 元 规格: 100ul
产品信息
- 产品编号
- bs-13355R-PE-Cy7
- 英文名称
- Anti-MBOAT4/PE-Cy7
- 中文名称
- PE-Cy7标记的脑肠肽O酰基转移酶/Ghrelin O acyltransferase抗体
- 别 名
- FKSG89; ghrelin o transferas; Ghrelin O-acyltransferase; GOAT; MBOA4_HUMAN; Mboat4; Membrane-bound O-acyltransferase domain-containing protein 4; O-acyltransferase (membrane bound) domain containing 4; O-acyltransferase domain-containing protein 4; OACT4.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Horse, Rabbit, Monkey, Gorilla
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 50kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Ghrelin O acyltransferase
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
MBOAT4 (membrane-bound O-acyltransferase domain-containing protein 4, Ghrelin O-acyltransferase) is a 435 amino acid, multi-pass membrane protein that belongs to the membrane-bound acyltransferase family. MBOAT4 functions as an enzyme that attaches an octanoate fatty acid to serine-3 of ghrelin. Ghrelin is a very small, appetite-stimulating hormone secreted by the food-deprived stomach. MBOAT4 can use a variety of fatty acids as substrates including octanoic acid, decanoic acid and tetradecanoic acid. MBOAT4 expression, consistent with its function, is mainly in the stomach and intestines. Due to its primary function, MBOAT4 is a candidate for obesity and appetite suppression studies.
Function:
Mediates the octanoylation of ghrelin at Ser-3. Can use a variety of fatty acids as substrates including octanoic acid, decanoic acid and tetradecanoic acid.
Subcellular Location:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Tissue Specificity:
Expressed predominantly in stomach with moderate levels in pancreas and relatively low levels in most other tissues.
Similarity:
Belongs to the membrane-bound acyltransferase family.
Database links:Entrez Gene: 619373 Human
Entrez Gene: 234155 Mouse
Omim: 611940 Human
SwissProt: Q96T53 Human
SwissProt: P0C7A3 Mouse
Unigene: 627194 Human
Unigene: 324008 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.