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货号: bs-13325R-PE-Cy7 基本售价: 2980.0 元 规格: 100ul
产品信息
- 产品编号
- bs-13325R-PE-Cy7
- 英文名称
- Anti-GDPD1/PE-Cy7
- 中文名称
- PE-Cy7标记的甘油磷酸二酯酶磷酸结构域4抗体
- 别 名
- 2610020H15Rik; GDE4; Glycerophosphodiester phosphodiesterase 4; glycerophosphodiester phosphodiesterase domain containing 1; RP23-352L3.1; GDPD1_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 信号转导 新陈代谢
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Cow, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 36kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human GDPD1/GDE4
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
GDE4 is a 314 amino acid cytoplasmic and multi-pass membrane protein that belongs to the glycerophosphoryl diester phosphodiesterase family. Expressed in small intestine, placenta, kidney, ovary, thymus, pancreas, spleen, liver and peripheral blood leukocytes, GDE4 contains one GDPD domain and exists as three alternatively spliced isoforms. GDE4 is encoded by a gene that maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1.
Function:
This gene encodes a member of the glycerophosphodiester phosphodiesterase family of enzymes that catalyze the hydrolysis of deacylated glycerophospholipids to glycerol phosphate and alcohol. Alternative splicing results in multiple transcript variants.
Subcellular Location:
Cytoplasm. Membrane; Multi-pass membrane protein (Potential).
Tissue Specificity:
Detected in placenta, liver, kidney, pancreas, spleen, thymus, ovary, small intestine and peripheral blood leukocytes.
Similarity:
Belongs to the glycerophosphoryl diester phosphodiesterase family.
Contains 1 GDPD domain.
Database links:Entrez Gene: 284161 Human
Entrez Gene: 66569 Mouse
Entrez Gene: 303407 Rat
SwissProt: Q8N9F7 Human
SwissProt: Q9CRY7 Mouse
SwissProt: Q0VGK4 Rat
Unigene: 631744 Human
Unigene: 281887 Mouse
Unigene: 138410 Ra
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.