产品中心
当前位置：首页>产品中心Anti-GEN1/PE-Cy7
货号： bs-13334R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-13334R-PE-Cy7
- 英文名称
- Anti-GEN1/PE-Cy7
- 中文名称
- PE-Cy7标记的GEN1蛋白抗体
- 别 名
- DKFZp781F0986; Flap endonuclease GEN homolog 1; FLJ40869; GEN 1; Gen; Gen homolog 1 endonuclease (Drosophila); Gen homolog 1 endonuclease; GEN_HUMAN; GEN1.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Cow, Horse, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 103kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human GEN1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Endonuclease which cleaves flap structures at the junction between single-stranded DNA and double-stranded DNA. Specific for 5-overhanging flap structures in which the 5-upstream of the flap is completely double-stranded. Prefers the blocked-flap structures similar to those occurring at replication forks, in which the 5 single-strand overhang of the flap is double-stranded.
Function:
Endonuclease which resolves Holliday junctions by the introduction of symmetrically related cuts across the junction point, to produce nicked duplex products in which the nicks can be readily ligated. Four-way DNA intermediates, also known as Holliday junctions, are formed during homologous recombination and DNA repair, and their resolution is necessary for proper chromosome segregation.
Subcellular Location:
Nucleus.
Similarity:
Belongs to the XPG/RAD2 endonuclease family. GEN subfamily.
Database links:
UniProtKB/Swiss-Prot: Q17RS7.2
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.