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货号： bs-13268R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-13268R-PE-Cy7
- 英文名称
- Anti-GALM/PE-Cy7
- 中文名称
- PE-Cy7标记的半乳糖脱氢酶抗体
- 别 名
- Aldose 1 epimerase; Aldose 1-epimerase; BLOCK25; Galactomutarotase; Galactose mutarotase; Galm; GALM_HUMAN; IBD1.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 新陈代谢
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Cow, Horse, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 38kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human GALM/Galactose mutarotase
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Galactose Mutarotase is a member of the aldose epimerase family and is involved in hexose metabolism. Through its catalytic activity, Galactose Mutarotase converts beta-aldose to alpha-aldose on several sugars, including D-glucose, L-arabinose and D-xylose. Found in the cytoplasm of most cells, Galactose Mutarotase plays a key role in galactose metabolism by catalyzing the conversion of beta-D-galactose to alpha-D-galactose. The enzyme contains two residues, Glu 304 and His 170, that are critical for catalysis, as well as His 96 and Asp 243, which are important for proper substrate recognition by the active site. No known diseases have been associated with mutations in the Galactose Mutarotase gene, although inhibition of Galactose Mutarotase activity could potentially be associated with a build-up of unmetabolized sugars during metabolism.
Function:
Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose.
Subunit:
Monomer.
Subcellular Location:
Cytoplasm.
Similarity:
Belongs to the aldose epimerase family.
Database links:Entrez Gene: 130589 Human
Entrez Gene: 319625 Mouse
Entrez Gene: 313843 Rat
Entrez Gene: 616676 Cow
Omim: 608883 Human
SwissProt: Q5EA79 Cow
SwissProt: Q96C23 Human
SwissProt: Q8K157 Mouse
SwissProt: Q66HG4 Rat
Unigene: 435012 Human
Unigene: 29098 Mouse
Unigene: 83639 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.