产品中心
当前位置：首页>产品中心Anti-GADL1/PE-Cy7
货号： bs-13264R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-13264R-PE-Cy7
- 英文名称
- Anti-GADL1/PE-Cy7
- 中文名称
- PE-Cy7标记的谷氨酸脱羧酶样蛋白1抗体
- 别 名
- GADL1; GADL1_HUMAN; Glutamate decarboxylase like 1; Glutamate decarboxylase-like protein 1; MGC138191; OTTHUMP00000161199; OTTHUMP00000222306.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 神经生物学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Bee,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 59kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human GADL1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
There are two forms of glutamic acid decarboxylases (GADs) that exist in brain: GAD-65 (also known as GAD2) and GAD-67 (also known as GAD1, GAD or SCP). GAD-65 and GAD-67 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate limiting step in the production of GABA (gamma-aminobutyric acid) from L-glutamic acid. Although both GADs are found in brain, GAD-65 localizes to synaptic vesicle membranes in nerve terminals, while GAD-67 is distributed throughout the cell. GAD-67 is responsible for the basal levels of GABA synthesis. In the case of a heightened demand for GABA in neurotransmission, GAD-65 transiently activates to assist in GABA production. As a member of the group II decarboxylase family, GADL1 (Glutamate decarboxylase-like protein 1) is a 521 amino acid protein that utilizes pyridoxal phosphate as a cofactor for its carboxylase activity. There are two isoforms of GADL1 that exist as a result of alternative splicing events.
Similarity:
Belongs to the group II decarboxylase family.
Database links:Entrez Gene: 614548 Cow
Entrez Gene: 485629 Dog
Entrez Gene: 100712617 Guinea pig
Entrez Gene: 100057562 Horse
Entrez Gene: 339896 Human
Entrez Gene: 73748 Mouse
Entrez Gene: 100623700 Pig
Entrez Gene: 367181 Rat
SwissProt: A6QM00 Cow
SwissProt: Q6ZQY3 Human
SwissProt: Q80WP8 Mouse
Unigene: 657052 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.