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货号： bs-13238R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-13238R-PE-Cy7
- 英文名称
- Anti-FYTTD1/PE-Cy7
- 中文名称
- PE-Cy7标记的FYTTD1蛋白抗体
- 别 名
- DKFZp761B1514; Forty two three domain containing 1; Forty two three domain containing protein 1; Forty-two-three domain-containing protein 1; FYTTD 1; fyttd1; OTTHUMP00000208028; OTTHUMP00000208031; OTTHUMP00000208032; Protein 40 2 3; Protein 40-2-3; UAP56 interacting factor; UAP56-interacting factor; UIF; UIF_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 36kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human FYTTD1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
FYTTD1 is a 318 amino acid protein belonging to the UIF family. FYTTD1 localizes to nucleus and is required for mRNA export from nucleus to cytoplasm. Functioning as an adaptor, FYTTD1 utilizes the BAT1/DDX39-TAP pathway, which is essential for efficient mRNA export and nuclear pore delivery. FYTTD1 interacts with SSRP1, a protein that is necessary for its recruitment of mRNAs, in addition to a mutually exclusive interaction with BAT1/DDX39 and TAP. FYTTD1 exists as four alternatively spliced isoforms and is encoded by a gene located on human chromosome 3q29.
Function:
Required for mRNA export from the nucleus to the cytoplasm. Acts as an adapter that uses the DDX39B/UAP56-NFX1 pathway to ensure efficient mRNA export and delivering to the nuclear pore. Associates with spliced and unspliced mRNAs simultaneously with THOC4.
Subunit:
Interacts with CHTOP (By similarity). Interacts with DDX39B/UAP56 and NXF1; interaction with DDX39B/UAP56 and NXF1 are mutually exclusive. Interacts with SSRP1; required for its recruitment to mRNAs.
Subcellular Location:
Nucleus; nucleoplasm. Nucleus speckle.
Similarity:
Belongs to the UIF family.
Database links:
UniProtKB/Swiss-Prot: Q96QD9.3
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.