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货号： bs-13187R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-13187R-PE-Cy7
- 英文名称
- Anti-FMO5/PE-Cy7
- 中文名称
- PE-Cy7标记的二甲基苯胺单加氧酶5抗体
- 别 名
- Dimethylaniline monooxygenase [N oxide forming] 5; Dimethylaniline monooxygenase [N-oxide-forming] 5; Dimethylaniline oxidase 5; FMO 5; FMO5; FMO5_HUMAN; Hepatic flavin containing monooxygenase 5; Hepatic flavin-containing monooxygenase 5.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 信号转导 新陈代谢
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 60kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human FMO5
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The Flavin containing monooxygenase family consists of five gene products, FMO1-5, that are major enzymatic oxidants involved in the metabolism of various therapeutics. Localizing to microsomal and endoplasmic reticulum membranes, FMO5 (flavin containing monooxygenase 5), also known as dimethylaniline monooxygenase [N-oxide-forming] 5, hepatic flavin-containing monooxygenase 5 or dimethylaniline oxidase 5, is a 533 amino acid protein belonging to the FMO family. Expressed in adult and fetal liver, FMO5 is unlike other FMO family members because it does not function as a drug-metabolizing enzyme. FMO5 binds FAD as a cofactor and is encoded by a gene located on human chromosome 1q21.1.
Function:
In contrast with other forms of FMO it does not seem to be a drug-metabolizing enzyme.
Subcellular Location:
Microsome membrane. Endoplasmic reticulum membrane.
Tissue Specificity:
Expressed in fetal and adult liver.
Similarity:
Belongs to the FMO family.
Database links:Entrez Gene: 2330Human
Entrez Gene: 14263Mouse
Entrez Gene: 246248Rat
Omim: 603957Human
SwissProt: P49326Human
SwissProt: P97872Mouse
SwissProt: Q8K4C0Rat
Unigene: 642706Human
Unigene: 385180Mouse
Unigene: 7038Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.