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货号： bs-15135R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-15135R-PE-Cy7
- 英文名称
- Anti-C22orf29/PE-Cy7
- 中文名称
- PE-Cy7标记的22号染色体开放阅读框29抗体
- 别 名
- C22orf29; CV029_HUMAN; Uncharacterized protein C22orf29.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 39kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human C22orf29
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Chromosome 22 contains over 500 genes and about 49 million bases. Being the second smallest human chromosome, 22 contains a surprising variety of interesting genes. Phelan-McDermid syndrome, neurofibromatosis type 2 and autism are associated with chromosome 22. A schizophrenia susceptibility locus has been identified on chromosome 22 and studies show that 22q11 deletion symptoms include a high incidence of schizophrenia. Translo-acations between chromosomes 9 and 22 may lead to the formation of the Philadelphia chromosome and the subsequent production of the novel fusion protein, Bcr-Abl, a potent cell proliferation activator found in several types of leukemia. The C22orf29 gene product has been provisionally designated C22orf29 pending further characterization
Function:
Could induce apoptosis in a BH3 domain-dependent manner.The direct interaction network of Bcl-2 family members may play akey role in modulation BOP intrinsic apoptotic signaling activity.
Subunit:
Interacts (via BH3 domain) with VDAC1. Interacts withpro-survival Bcl-2 family members, BCL2, BCL2L1 isoform Bcl-X(L),MCL1, BCL2A1 and BCL2L2. Interacts with BAX and BAK.
Subcellular Location:
Mitochondrion.
Tissue Specificity:
Ubiquitously expressed.
Database links:Entrez Gene: 79680Human
SwissProt: Q7L3V2 Human
Unigene: 105642Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.