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货号： bs-12995R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-12995R-PE-Cy7
- 英文名称
- Anti-DNASE1L1/PE-Cy7
- 中文名称
- PE-Cy7标记的DNA酶1样蛋白1抗体
- 别 名
- Deoxyribonuclease I-like 1; Deoxyribonuclease I like 1; Deoxyribonuclease-1-like 1; DNAS1L1; DNase I like 1; DNase I like muscle specific; DNase I lysosomal like; DNase I-like 1; DNase X; DNASE1L1; DNASEX; DNL1L; DNSL1_HUMAN; Muscle specific DNase I like; DNASEX; Muscle-specific DNase I-like; XIB.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 染色质和核信号 神经生物学 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Horse,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 32kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human DNASE1L1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
DNASE1L1 is a 302 amino acid protein that localizes to the endoplasmic reticulum and belongs to the deoxyribonuclease family. Expressed at high levels in cardiac and skeletal muscle and at lower levels in a variety of tissues throughout the body, DNASE1L1 exists as multiple alternatively spliced isoforms and is thought to function in a similar manner to DNase l, possibly mediating internucleosomal DNA degradation via catalytic cleavage events. The gene encoding DNASE1L1 maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes. In conjunction with chromosome Y, chromosome X is responsible for sex determination. There are a number of conditions related to an abnormal number and combination of sex chromosomes, some of which include Turners syndrome, color blindness, hemophilia and Duchenne muscular dystrophy.
Subcellular Location:
Endoplasmic reticulum.
Tissue Specificity:
Highest levels in skeletal and cardiac muscles. Detectable in all other tissues tested except brain.
Similarity:
Belongs to the DNase I family.
Database links:
UniProtKB/Swiss-Prot: P49184.1
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.