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货号： bs-12888R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-12888R-PE-Cy7
- 英文名称
- Anti-BRD2/PE-Cy7
- 中文名称
- PE-Cy7标记的BRD2蛋白抗体
- 别 名
- BRD 2; Brd2; BRD2_HUMAN; Bromodomain containing 2; BROMODOMAIN CONTAINING PROTEIN2; Bromodomain-containing protein 2; D6S113E; DKFZp686N0336; female sterile homeotic related gene 1; FLJ31942; FSH; FSRG1; KIAA9001; NAT; O27.1.1; Really interesting new gene 3 protein; Ring3; RING3 PROTEIN; RNF3.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 信号转导 激酶和磷酸酶 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 88kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human BRD2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The bromodomain-containing proteins include BRD2, BRD3, BRD4 and BRDT. BRD2 (RING3 protein) is a mitogen-activated nuclear protein whose gene is located in the human MHC II region, suggesting its relation to HLA-associated diseases. The gene encoding BRD3 (RING3-like protein) contains two bromodomains and maps to chromosome 9q34. BRD4 (HUNK1 protein) is a nuclear protein involved in the regulation of chromosomal dynamics during mitosis. The testis-specific bromodomain protein BRDT contains a PEST sequence, indicating that it undergoes rapid intracellular degradation. The bromodomain-containing proteins are ubiquitously expressed.
Function:
May play a role in spermatogenesis or folliculogenesis.
Subunit:
Homodimer. Interacts with E2F1 and with histone H4acetylated at Lys-13.
Subcellular Location:
Nucleus.
Similarity:
Contains 2 bromo domains.
Contains 1 ET domain.
Database links:Entrez Gene: 6046 Human
Entrez Gene: 14312 Mouse
Entrez Gene: 294276 Rat
Omim: 601540 Human
SwissProt: P25440 Human
SwissProt: Q7JJ13 Mouse
SwissProt: Q6MGA9 Rat
Unigene: 75243 Human
Unigene: 3444 Mouse
Unigene: 98146 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.