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货号： bs-12462R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-12462R-PE-Cy7
- 英文名称
- Anti-AGPS/PE-Cy7
- 中文名称
- PE-Cy7标记的烷基甘油酮磷酸合酶抗体
- 别 名
- AAG5; ADAP-S; ADAS; ADAS_HUMAN; ADHAPS; ADPS; Aging associated gene 5 protein; Aging-associated gene 5 protein; AGPS; ALDHPSY; Alkyl-DHAP synthase; Alkyldihydroxyacetonephosphate synthase; Alkyldihydroxyacetonephosphate synthase, peroxisomal; Alkylglycerone phosphate synthase; Alkylglycerone-phosphate synthase; peroxisomal.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 神经生物学 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Cow, Horse,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 67kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human AGPS/Alkyl-DHAP synthase
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene is a member of the FAD-binding oxidoreductase/transferase type 4 family. It encodes a protein that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetonephosphate (DHAP) is converted to alkyl-DHAP by the addition of a long chain alcohol and the removal of a long-chain acid anion. The protein is localized to the inner aspect of the peroxisomal membrane and requires FAD as a cofactor. Mutations in this gene have been associated with rhizomelic chondrodysplasia punctata, type 3 and Zellweger syndrome. [provided by RefSeq, Jul 2008]
Function:
Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids.
Subunit:
Homodimer.
Subcellular Location:
Peroxisome membrane. Localized to the inner aspect of the peroxisomal membrane.
DISEASE:
Defects in AGPS are the cause of rhizomelic chondrodysplasia punctata type 3 (RCDP3) [MIM:600121]. RCDP3 is characterized by rhizomelic shortening of femur and humerus, vertebral disorders, cataract, cutaneous lesions and severe mental retardation.
Similarity:
Belongs to the FAD-binding oxidoreductase/transferase type 4 family.
Contains 1 FAD-binding PCMH-type domain.
Database links:Entrez Gene: 8540 Human
Entrez Gene: 228061 Mouse
Entrez Gene: 84114 Rat
Omim: 603051 Human
SwissProt: O00116 Human
SwissProt: Q8C0I1 Mouse
SwissProt: Q9EQR2 Rat
Unigene: 516543 Human
Unigene: 31227 Mouse
Unigene: 40603 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.