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货号： bs-12465R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-12465R-PE-Cy7
- 英文名称
- Anti-Alpha SNAP/PE-Cy7
- 中文名称
- PE-Cy7标记的可溶性附着蛋白α-SNAP抗体
- 别 名
- Alpha soluble NSF attachment protein; Alpha-soluble NSF attachment protein; N ethylmaleimide sensitive factor attachment protein alpha; N-ethylmaleimide-sensitive factor attachment protein alpha; NAPA; SNAA_HUMAN; SNAP alpha; SNAP alpha; SNAP-alpha; SNAPA.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 转运蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 33kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Alpha SNAP
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Syntaxins were originally thought to be docking proteins, but have more recently been categorized as anchoring proteins that anchor themselves to the cytoplasmic surfaces of cellular membranes. Syntaxins have been shown to bind to various proteins involved in exocytosis, including VAMPs (vesicle-associated membrane proteins), NSF (N-ethylmaleimide-sensitive factor), SNAP 25 (synaptosomal-associated protein of 25kDa), SNAPs (soluble NSF attachment proteins) and synaptotagmin. VAMPs (also designated synaptobrevins), including VAMP-1 and VAMP-2, and synaptotagmin, a protein that may function as an inhibitor of exocytosis, are vesicular proteins.
Function:
Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.
Subunit:
Interacts with PRKCABP, and disrupts the interaction between GRIA2 and PRKCABP, leading to the internalization of GRIA2. Found in a complex with VAMP8 (By similarity). Component of a SNARE-like complex that contains at least ZW10, USE1L, RINT1, STX18 and NAPA/SNAP-alpha. Interacts with VTI1A. Interacts with STX12 (By similarity).
Subcellular Location:
Membrane; Peripheral membrane protein.
Similarity:
Belongs to the SNAP family.
Database links:Entrez Gene: 518407 Cow
Entrez Gene: 8775 Human
Entrez Gene: 108124 Mouse
Entrez Gene: 140673 Rat
Omim: 603215 Human
SwissProt: P81125 Cow
SwissProt: P54920 Human
SwissProt: Q9DB05 Mouse
SwissProt: P54921 Rat
Unigene: 126938 Human
Unigene: 727492 Human
Unigene: 104540 Mouse
Unigene: 431371 Mouse
Unigene: 31745 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.