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货号： bs-12467R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-12467R-PE-Cy7
- 英文名称
- Anti-AMBN/PE-Cy7
- 中文名称
- PE-Cy7标记的釉基质蛋白抗体
- 别 名
- AMBN; AMBN_HUMAN; Ameloblastin (enamel matrix protein); Ameloblastin.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 细胞骨架 细胞外基质
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 45kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human AMBN
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Dental enamel is a highly mineralized tissue with most of its volume occupied by large, highly organized, hydroxyapatite crystals. This structure is thought to be controlled through the interaction of many organic matrix molecules including amelogenin, ameloblastin, enamelin, tuftelin and several other enzymes. All of these secreted proteins are involved in the mineralization and enamel matrix formation in developing tooth enamel. Ameloblastin (AMBN), which localizes to the extracellular matrix, is an ameloblast-specific protein. It is detected in the sheath space between rod-interrod enamel and at the Tomes processes of secretory ameloblasts. Defects in the gene encoding for ameloblastin, AMBN, can be seen in patients with ameloblastomas.
Function:
Involved in the mineralization and structural organization of enamel.
Subcellular Location:
Secreted > extracellular space > extracellular matrix.
Tissue Specificity:
Ameloblast-specific. Located at the Tomes processes of secretory ameloblasts and in the sheath space between rod-interrod enamel.
Similarity:
Belongs to the ameloblastin family.
Database links:Entrez Gene: 258 Human
Omim: 601259 Human
SwissProt: Q9NP70 Human
Unigene: 272396 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.