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货号： bs-12370R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-12370R-PE-Cy7
- 英文名称
- Anti-FAM65B/PE-Cy7
- 中文名称
- PE-Cy7标记的FAM65B蛋白抗体
- 别 名
- Ab2 162; C6orf32; DIFF48; FA65B_HUMAN; Fam65b; KIAA0386; PL48; Protein FAM65B.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 发育生物学 干细胞 糖尿病
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 118kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human FAM65B
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Making up nearly 6% of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinsons disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6. The C6orf32 gene product has been provisionally designated C6orf32 pending further characterization.
Function:
Isoform 2 play a role in promoting myogenic cell differentiation, cytoskeletal rearrangement and filopodia formation.
Subcellular Location:
Mitochondrion and Cytoplasm; cytoskeleton. Cell projection; filopodium. Detected in cellular filopodia.
Tissue Specificity:
Isoform 1 is present in the brain. Isoform 2 is expressed during differentiation of fetal primary myoblasts. Also shows marked expression during cytotrophoblast differentiation.
Post-translational modifications:
Asn-41 was reported (PubMed:16335952) to be N-glycosylated; however as this position is probably not extracellular, the in vivo relevance is not proven.
Similarity:
Belongs to the FAM65 family.
Database links:
UniProtKB/Swiss-Prot: Q9Y4F9.4
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.