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货号： bs-12216R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-12216R-PE-Cy7
- 英文名称
- Anti-ZNF3/PE-Cy7
- 中文名称
- PE-Cy7标记的锌指蛋白3抗体
- 别 名
- A8 51; C2 H2 type zinc finger protein; FLJ20216; HF.12; HZF3.1; KOX25; PP838; Zfp113; Zinc finger protein 3 (A8 51); Zinc finger protein 3; Zinc finger protein HF.12; Zinc finger protein KOX25; ZNF3_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 转录调节因子 锌指蛋白 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 51kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from Human ZNF3
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.
- 产品介绍
- background:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kruppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF3, also known as KOX25, is a zinc finger protein belonging to the Kruppel C(2)H(2)-type zinc finger protein family. It localizes to the nucleus and is involved in cell differentiation and proliferation. ZNF3 is a 446 amino acid long protein that contains eight C(2)H(2)-type zinc fingers and one KRAB domain. ZNF3 is located in a cluster of KOX zinc-finger genes found on chromosome 10.
Function:
A zinc finger is a protein domain that can bind to DNA. A zinc finger consists of two antiparallel ?sheets, and an alpha helix. The structure of each individual finger is highly conserved and consists of about 30 amino acid residues, constructed as a 哌alpha fold and held together by the zinc ion. The alpha helix occurs at the C terminal part of the finger, while the ?sheet occurs at the N terminal part.
Subcellular Location:
Nuclear
Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 8 C2H2-type zinc fingers.
Contains 1 KRAB domain.
Database links:Entrez Gene: 7551 Human
Omim: 194510 Human
SwissProt: P17036 Human
Unigene: 435302 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.