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货号： bs-12135R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-12135R-PE-Cy7
- 英文名称
- Anti-Striatin 3/PE-Cy7
- 中文名称
- PE-Cy7标记的细胞周期蛋白SG2N抗体
- 别 名
- Striatin3; Striatin-3; Striatin 3; Cell cycle autoantigen SG2NA; Cell cycle S/G2 nuclear autoantigen; GS2NA; nuclear autoantigen; S/G2 antigen; SG2NA; Striatin 3; Striatin, calmodulin binding protein 3; STRN3_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 神经生物学 信号转导 细胞周期蛋白 细胞膜受体 结合蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 87kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Striatin 3/SG2NA
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Striatin, SG2NA, and zinedin, the three mammalian members of the striatin family, are multimodular, WD repeat and calmodulin-binding proteins. Zinedin and SG2NA share with striatin identical protein-protein interaction domains and the same overall domain structure. All three proteins are both cytosolic and membrane-bound and bind calmodulin in the presence of calcium. Striatin is a neuronal, intracellular protein strictly expressed in the somato-dendritic compartment, including spines and subsets of neurons, and is considered as a marker of neuronal polarity. Downregulation of striatin, which is expressed in a few subsets of neurons, impairs the growth of dendrites as well as rat locomotor activity. Zinedin is mainly expressed in the central nervous system, whereas SG2NA is mainly expressed in the brain and muscle.
Function:
Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein.
Subunit:
Interacts with protein phosphatase 2A (PP2A) (Potential).
Subcellular Location:
Cytoplasm. Membrane; Peripheral membrane protein.
Similarity:
Belongs to the WD repeat striatin family.
Contains 6 WD repeats.
Database links:Entrez Gene: 29966Human
Entrez Gene: 94186Mouse
Entrez Gene: 114520Rat
SwissProt: Q13033Human
SwissProt: Q9ERG2Mouse
SwissProt: P58405Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.