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货号： bs-12118R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-12118R-PE-Cy7
- 英文名称
- Anti-SLC35C2/PE-Cy7
- 中文名称
- PE-Cy7标记的溶质载体蛋白家族35成员C2抗体
- 别 名
- BA394O2.1; C20orf5; CGI-15; FLJ37039; MGC20633; MGC32079; MGC39183; Ovarian cancer-overexpressed gene 1 protein; OVCOV1; S35C2_HUMAN; SLC35C2; Solute carrier family 35 member C2.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 心血管 细胞生物 神经生物学 信号转导 新陈代谢
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 40kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human SLC35C2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
SLC35C2 (solute carrier family 35, member C2), also known as C20orf5, OVCOV1 or CGI-15, is a 365 amino acid multi-pass membrane protein that belongs to the TPT transporter family and exists as multiple alternatively spliced isoforms. Expressed ubiquitously and functionally induced in hypoxic trophoblast cells, SLC35C2 plays a role in the cellular response to tissue hypoxia and is thought to be involved in the pathogenesis of ovarian cancer. The gene encoding SLC35C2 maps to human chromosome 20, which houses over 600 genes some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought important for seminal production and may be potential targets for male contraception.
Function:
May play an important role in the cellular response to tissue hypoxia.
Subcellular Location:
Membrane.
Tissue Specificity:
Ubiquitously expressed although the level of expression is tissue dependent. Overexpressed in ovarian cancer.
Similarity:
Belongs to the TPT transporter family. SLC35C subfamily.
Database links:Entrez Gene: 514485 Cow
Entrez Gene: 609863 Dog
Entrez Gene: 100056733 Horse
Entrez Gene: 51006 Human
Entrez Gene: 228875 Mouse
Entrez Gene: 100152375 Pig
Entrez Gene: 100349356 Rabbit
Entrez Gene: 311637 Rat
Entrez Gene: 323482 Zebrafish
SwissProt: Q9NQQ7 Human
SwissProt: Q8VCX2 Mouse
Unigene: 593344 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.