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货号： bs-12110R-PE-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-12110R-PE-Cy7
- 英文名称
- Anti-P2RX6/PE-Cy7
- 中文名称
- PE-Cy7标记的三磷酸腺苷受体P2X6抗体
- 别 名
- ATP receptor; P2RX6; P2RX6_HUMAN; P2RXL1; P2X purinoceptor 6; P2X6; P2XM; Purinergic receptor; Purinergic receptor P2X like 1; Purinergic receptor P2X-like 1; Skeletal muscle expressed P2X.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 神经生物学 信号转导 细胞凋亡 通道蛋白 细胞膜受体 新陈代谢
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Horse, Rabbit,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 49kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human P2RX6
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The P2X receptor family is comprised of ligand-gated ion channels that allow for the increased permeability of calcium into the cell in response to extracellular ATP. The seven P2X receptors, P2X1-P2X7, form either homomeric or heteromeric channels or both. They are characterized by intracellular amino- and carboxy-termini. P2X receptors are expressed in a wide variety of tissues, including neurons, prostate, bladder, pancreas, colon, testis and ovary. The major function of the P2X receptors is to mediate synaptic transmissions between neurons and to other tissues via the binding of extracellular ATP, which acts as a neurotransmitter. The P2X receptors may be involved in the onset of necrosis or apoptosis after prolonged exposure to high concentrations of extracellular ATP.
Function:
Receptor for ATP that acts as a ligand-gated ion channel.
Subunit:
Functional P2XRs are organized as homomeric and heteromeric trimers
Subcellular Location:
Membrane; Multi-pass membrane protein.
Tissue Specificity:
Expressed predominantly in skeletal muscle.
Similarity:
Belongs to the P2X receptor family.
Database links:Entrez Gene: 9127 Human
Entrez Gene: 18440 Mouse
Entrez Gene: 25041 Rat
Omim: 608077 Human
SwissProt: O15547 Human
SwissProt: O54803 Mouse
SwissProt: P51579 Rat
Unigene: 113275 Human
Unigene: 8032 Mouse
Unigene: 10258 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.